β-Endorphin (1-27), human CAS NO.76622-84-9

β-Endorphin (1-27), human CAS NO.76622-84-9

β-Endorphin (1-27), human CAS NO.76622-84-9

β-Endorphin (1-27), human CAS NO.76622-84-9

β-Endorphin (1-27), human CAS NO.76622-84-9

β-Endorphin (1-27), human is a natur全てy occurring N-terminal fragment of the full-length β-endorphin peptide, functioning as a potent endogenous opioid receptor antagonist. Unlike many analgesic peptides, it competitively binds to μ-, δ-, and κ-opioid receptors to block signaling, making it a critical re検索 tool for studying pain modulation, receptor dynamics, and the endogenous opioid system in neuroscience and pharmacology laboratories.



TECHNICAL SPECIFICATIONS


Item
Specification
製品 名前
β-Endorphin (1-27), human
CAS NO.
76622-84-9
Appearance
White to off-white lyophilized powder
Molecular Formula
C₁₃₉H₂₁₇N₃₃O₄₀S
Molecular Weight
3180.5g/mol
Purity (RP-HPLC)
≥95% 
Solubility

Soluble in 1M acetic acid, DMSO, or deionized water

Endotoxin
≤1 EU/mg 
Biological Activity
Potent antagonist at μ, δ, and κ opioid receptors
Storage Conditions
Store at -20°C, protected from light and moisture
Stock 位置
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Endomorphin-2 exerts its effects by selectively binding to μ-opioid receptors with high affinity, thereby activating G-protein coupled signaling pathways that inhibit adenylate cyclase and reduce cAMP 製品ion. This action leads to the hyperpolarization of neurons and inhibition of neurotransmitter release, effectively blocking pain signal transmission in both the central and peripheral nervous systems. Its mechanism is distinct in its ability to induce the release of other endogenous opioids like dynorphin A, contributing to its complex analgesic profile in preclinical models.

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2.製品 INDICATIONS

This 製品 is strictly indicated for re検索 use in biochemical and pharmacological studies, including receptor binding assays, signal transduction re検索, and in vitro functional characterization of μ-opioid receptor activity. It is particularly valuable for scientists investigating spinal cord-mediated analgesia, neuropathic pain mechanisms, and opioid receptor pharmacology. The peptide is also employed in the screening and development of new analgesic drugs and in studies exploring the physiological roles of endogenous opioid systems.

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3.CLINICAL EFFICACY OF 製品

As a re検索 biochemical, β-Endorphin (1-27) is not intended for human therapeutic use. Its efficacy is demonstrated in preclinical re検索 settings, where it has been shown to effectively reverse or 前後ent analgesia induced by full-length β-endorphin and other opioid agonists in animal models, providing robust data on the modulation of nociceptive thresholds and the physiological role of endogenous opioid fragments.

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4.証明書

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide 製品, adhering strictly to quality standards and obtaining internation全てy recognized 認証s.


私たちの製品ion partners 全て employ GMP-compliant 製品ion systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of 製品 comes with complete documentation, including a 証明書 of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and re検索-grade peptide 製品 to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging 解決 to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the 製品.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the 製品ion and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The 会社 invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA 認証s, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality 製品 and superior services.


We focus on the re検索 and development and supply of high-quality chemical 製品, strictly adhering to international standards and quality systems. 私たちの製品s are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific re検索, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot タグ: BetaEndorphin127, #OpioidReceptorAntagonist, #EndogenousOpioid, #PainRe検索, #NeuroscienceReagent, #PeptideAntagonist, #MuDeltaKappaOpioid, #Re検索Peptide, #Neuropharmacology, #CAS76622849

If you have any 製品 requirements, please 送信 an メール to:support@huanqiukeji9.com;whatsapp:85244969439

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