β-Endorphin (6-31), human CAS NO.77761-27-4

β-Endorphin (6-31), human CAS NO.77761-27-4

β-Endorphin (6-31), human CAS NO.77761-27-4

β-Endorphin (6-31), human CAS NO.77761-27-4

β-Endorphin (6-31), human CAS NO.77761-27-4

β-Endorphin (6-31), human is a bioactive C-terminal fragment derived from the endogenous opioid peptide β-Endorphin. This 26-amino acid peptide retains the core receptor-binding region, functioning as a potent ligand for μ-opioid receptors (MOR). It is widely utilized in neuroscience and pharmacology re検索 to study pain signaling pathways, stress responses, and the molecular mechanisms of opioid receptor activation, serving as a critical tool for investigating endogenous analgesia and emotional regulation.



TECHNICAL SPECIFICATIONS


Item
Specification
製品 名前
β-Endorphin (6-31), human
CAS NO.
77761-27-4
Appearance
White to off-white lyophilized powder
Molecular Formula
C₁₃₁H₂₁₈N₃₄O₄₀
Molecular Weight
2968.4g/mol
Purity (RP-HPLC)
≥98% 
Solubility

Soluble in 1M acetic acid, DMSO, or deionized water

Endotoxin
≤1 EU/mg 
Biological Activity
Potent agonist for μ-opioid receptors (MOR)
Storage Conditions
Store at -20°C, protected from light and moisture
Stock 位置
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

The peptide exerts its effects by selectively binding to μ-opioid receptors in the central and peripheral nervous systems. Upon binding, it activates Gi/o protein-coupled signaling pathways, leading to the inhibition of adenylate cyclase and a reduction in intracellular cAMP levels. This action results in the hyperpolarization of neurons through the modulation of ion channels (inhibition of voltage-gated calcium channels and activation of potassium channels), ultima電話y suppressing neurotransmitter release and blocking pain signal transmission along nociceptive pathways.

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2.製品 INDICATIONS

This 製品 is specific全てy indicated for re検索 use only (RUO), targeting scientists in the fields of neuropharmacology and pain re検索. It is employed in a variety of experimental 応用s, including receptor binding assays, signal transduction studies, and the investigation of stress-related behaviors. Re検索ers also use it to explore the crosstalk between the nervous and immune systems, as well as in the screening and development of novel analgesic compounds with potenti全てy reduced side-effect profiles.

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3.CLINICAL EFFICACY OF 製品

As a re検索-grade biochemical reagent, β-Endorphin (6-31) is not intended for direct clinical or therapeutic use in humans. Its efficacy is demonstrated in preclinical re検索 settings, where it has been shown to produce significant analgesic and anti-nociceptive effects in animal models. These studies help elucidate the role of endogenous opioid systems in pain management and contribute to the foundational knowledge required for future drug discovery efforts aimed at treating chronic pain conditions.

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4.証明書

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide 製品, adhering strictly to quality standards and obtaining internation全てy recognized 認証s.


私たちの製品ion partners 全て employ GMP-compliant 製品ion systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of 製品 comes with complete documentation, including a 証明書 of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and re検索-grade peptide 製品 to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging 解決 to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the 製品.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the 製品ion and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The 会社 invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA 認証s, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality 製品 and superior services.


We focus on the re検索 and development and supply of high-quality chemical 製品, strictly adhering to international standards and quality systems. 私たちの製品s are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific re検索, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot タグ: BetaEndorphin631, #HumanBetaEndorphinFragment, #MuOpioidReceptor, #OpioidPeptide, #PainRe検索, #Neuropharmacology, #AnalgesicRe検索, #EndogenousOpioid, #Re検索Peptide, #NeuroscienceReagent

If you have any 製品 requirements, please 送信 an メール to:support@huanqiukeji9.com;whatsapp:85244969439

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